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There have also been combined final results from trials with regards to the utility of TMB. To this point, no possible scientific trials experienced demonstrated that choice of ICI cure based on a large TMB over reduced TMB improves OS.1,ten Most studies have evaluated TMB in distinct tumors sorts, whereas KEYNOTE-158 evaluated TMB retrospectively

There have also been mixed final results from trials with regards to the utility of TMB. Thus far, no future medical trials had demonstrated that selection of ICI remedy determined by a significant TMB more than very low TMB enhances OS.one,ten Most reports have evaluated TMB in distinct tumors varieties, While KEYNOTE-158 evaluated TMB retrospecti